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Equity Incentive Plans and Stock-Based Compensation - Summary of Black-Scholes Option Pricing Model to Estimate Stock-based Compensation Expense for Stock Option Awards (Details) - Incentive Stock Options and Nonqualified Stock Options - $ / shares
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected volatility, minimum 74.48% 74.95%
Expected volatility, maximum 75.01% 75.72%
Risk-free interest rate, minimum 1.64% 0.61%
Risk-free interest rate, maximum 2.13% 1.06%
Expected dividend 0.00% 0.00%
Minimum    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term (in years) 6 years 7 days 5 years 9 months 7 days
Underlying common stock fair value (USD per share) $ 7.56 $ 26.13
Maximum    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]    
Expected term (in years) 6 years 29 days 6 years 29 days
Underlying common stock fair value (USD per share) $ 12.68 $ 38.23