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Net Loss Per Share Attributable to Common Stockholders
 3 Months Ended
Mar. 31, 2022
Earnings Per Share [Abstract]  
Net Loss Per Share Attributable to Common Stockholders Net Loss Per Share Attributable to Common Stockholders
The following outstanding shares of potentially dilutive securities were excluded from the computation of diluted net (loss)/income per share attributable to common stockholders for the periods presented, because including them would have been antidilutive:
Three Months Ended March 31,
20222021
Options to purchase common stock5,196,869 3,928,287 
Restricted stock awards granted and not purchased— 4,195 
Unvested restricted shares6,235 96,245 
Total5,203,104 4,028,727 
A reconciliation of the numerator and denominator used in the calculation of the basic and diluted net loss per share attributable to common stockholders is as follows (in thousands, except share and per share amounts):
Three Months Ended March 31,
20222021
Net loss per share:  
Numerator  
Net loss$(28,100)$(22,856)
Denominator
Weighted-average common shares outstanding used to calculate net loss per share attributable to common stockholders:
Basic36,116,440 35,645,205 
Diluted36,116,440 35,645,205 
Net loss per share attributable to common stockholders:
Basic$(0.78)$(0.64)
Diluted$(0.78)$(0.64)