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Adimab Development and Option Agreement (the "Adimab Agreement") - Additional Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Research and Development Arrangement, Contract to Perform for Others [Line Items]      
Research and development expense $ 77,549 $ 66,193 $ 47,353
FTE costs | Adimab Agreement      
Research and Development Arrangement, Contract to Perform for Others [Line Items]      
Research and development expense $ 28 $ 200 $ 200