X0306 4 2022-09-14 0001746473 PLIANT THERAPEUTICS, INC. PLRX 0001768011 Knobil Katharine C/O PLIANT THERAPEUTICS, INC. 260 LITTLEFIELD AVENUE SOUTH SAN FRANCISCO CA 94080 true Stock Option (Right to Buy) 24.23 2022-09-14 4 A 0 30000 0 A 2032-09-13 Common Stock 30000 30000 D 1/36th of the shares subject to such option vest and become exercisable in substantially equal installments on each monthly anniversary of September 14, 2022, subject to the Reporting Person's continuous service to the Issuer on each such date. /s/ Mike Ouimette, attorney-in-fact 2022-09-16