<?xml version="1.0" encoding="UTF-8"?>
<edgarSubmission xmlns="http://www.sec.gov/edgar/thirteenffiler" xmlns:com="http://www.sec.gov/edgar/common">
  <schemaVersion>X0202</schemaVersion>
  <headerData>
    <submissionType>13F-HR</submissionType>
    <filerInfo>
      <liveTestFlag>LIVE</liveTestFlag>
      <flags>
        <confirmingCopyFlag>false</confirmingCopyFlag>
        <returnCopyFlag>true</returnCopyFlag>
        <overrideInternetFlag>false</overrideInternetFlag>
      </flags>
      <filer>
        <credentials>
          <cik>0001745981</cik>
          <ccc>XXXXXXXX</ccc>
        </credentials>
      </filer>
      <periodOfReport>12-31-2025</periodOfReport>
    </filerInfo>
  </headerData>
  <formData>
    <coverPage>
      <reportCalendarOrQuarter>12-31-2025</reportCalendarOrQuarter>
      <filingManager>
        <name>WORLDQUANT MILLENNIUM ADVISORS LLC</name>
        <address>
          <com:street1>399 PARK AVENUE</com:street1>
          <com:city>NEW YORK</com:city>
          <com:stateOrCountry>NY</com:stateOrCountry>
          <com:zipCode>10022</com:zipCode>
        </address>
      </filingManager>
      <reportType>13F HOLDINGS REPORT</reportType>
      <form13FFileNumber>028-18889</form13FFileNumber>
      <provideInfoForInstruction5>Y</provideInfoForInstruction5>
      <additionalInformation>The Institutional Investment Manager filing this report is a relying adviser (as defined under the SEC's Form ADV) of Millennium Management LLC. Certain holdings included in this report involve discretion exercised by one or more relying advisers of Millennium Management LLC, affiliated with the Institutional Investment Manager, that are not separately identified on this report.</additionalInformation>
    </coverPage>
    <signatureBlock>
      <name>Gil Raviv</name>
      <title>Global General Counsel</title>
      <phone>2128414100</phone>
      <signature>/s/ Gil Raviv</signature>
      <city>New York</city>
      <stateOrCountry>NY</stateOrCountry>
      <signatureDate>02-17-2026</signatureDate>
    </signatureBlock>
    <summaryPage>
      <otherIncludedManagersCount>1</otherIncludedManagersCount>
      <tableEntryTotal>568</tableEntryTotal>
      <tableValueTotal>25775456574</tableValueTotal>
      <isConfidentialOmitted>false</isConfidentialOmitted>
      <otherManagers2Info>
        <otherManager2>
          <sequenceNumber>1</sequenceNumber>
          <otherManager>
            <cik>0001273087</cik>
            <form13FFileNumber>028-10684</form13FFileNumber>
            <name>MILLENNIUM MANAGEMENT LLC</name>
          </otherManager>
        </otherManager2>
      </otherManagers2Info>
    </summaryPage>
  </formData>
</edgarSubmission>
