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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
CASH FLOWS FROM OPERATING ACTIVITIES    
Net loss $ (109,331) $ (56,914)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 15,054 9,642
Depreciation 2 22
Non-cash lease expense 124 115
Net amortization of premiums and discounts on short-term investments (6,369) (2,639)
Amortization of debt issuance costs and discount 269 212
Fair value change in warrant liability 487 110
Write-off of deferred offering costs   337
Unrealized foreign exchange gain and loss (19) (20)
Acquired in-process research and development expense 999  
Changes in operating assets and liabilities:    
Prepaid expenses and other assets (5,734) (372)
Accounts payable 7,549 2,245
Accrued expenses and other current liabilities 4,501 352
Operating lease liability (125) (111)
Net cash used in operating activities (92,593) (47,021)
CASH FLOWS FROM INVESTING ACTIVITIES    
Purchase of short-term and long-term marketable securities (378,383) (213,712)
Proceeds from maturities of short-term marketable securities 181,335 103,000
Purchase of in-process research and development (999)  
Net cash used in investing activities (198,047) (110,712)
CASH FLOWS FROM FINANCING ACTIVITIES    
Proceeds from the exercise of stock options 1,772 2,011
Proceeds from the issuance of common stock pursuant to employee stock purchase plan purchases 324 313
Proceeds from the issuance of common in a follow-on public offering 344,839  
Proceeds from the issuance of common stock pursuant to the ATM offering 10,604 124,212
Proceeds from the issuance of common stock pursuant to registered direct offering   211,217
Proceeds from loan payable 10,000 15,000
Payment of debt and equity issuance costs (751) (745)
Net cash provided by financing activities 366,788 352,008
Net increase in cash, cash equivalents and restricted cash 76,148 194,275
Cash, cash equivalents and restricted cash at the beginning of the period 234,207 249,881
Cash, cash equivalents and restricted cash at the end of the period 310,355 444,156
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:    
Cash paid for interest 1,861 949
NON-CASH INVESTING AND FINANCING INFORMATION:    
Change in net unrealizable loss on marketable securities $ (531) $ (288)
Warrant liability costs reclassified to additional paid-in equity on vested warrants issued 431 330
Debt and equity issuance costs included in accounts payable and accrued expenses and other current liabilities $ 64 $ 206
Deferred offering costs reclassified to additional paid-in equity   $ 364