Sale of Nonfinancial Assets - Additional Information (Details) - USD ($) $ in Thousands		3 Months Ended	6 Months Ended
	Mar. 31, 2022	Jun. 30, 2022	Jun. 30, 2022	May 31, 2022	Mar. 04, 2022	Dec. 31, 2021	[1]
Asset Acquisition [Line Items]
Proceeds from sale of priority review voucher			$ 110,000
Loss on sale of certain assets			6,261
Intangible assets, net		$ 29,908	29,908			$ 44,934
Priority Review Voucher
Asset Acquisition [Line Items]
Definitive agreement to sell				$ 110,000
Proceeds from sale of priority review voucher			110,000
Gain recognized, net of transactions costs		107,900	107,900
Origin-Sentynl APA
Asset Acquisition [Line Items]
Upfront payment received	$ 10,000
Intangible assets, net		$ 16,300	16,300
Origin-Sentynl APA | Other income (expense), net
Asset Acquisition [Line Items]
Loss on sale of certain assets			$ 6,300
Origin-Sentynl APA | Maximum [Member]
Asset Acquisition [Line Items]
Potential sales milestone payments					$ 4,500

[1] The condensed consolidated balance sheet as of December 31, 2021 is derived from the audited consolidated financial statements as of that date.