Restructuring, Impairment and Related Charges (Tables)

6 Months Ended

Jun. 30, 2022

Restructuring and Related Activities [Abstract]

Summary of Restructuring, Impairment and Related Charges

Restructuring, impairment and related charges included in our condensed statement of operations for the three and six months ended June 30, 2022 consisted of the following:

	Three Months Ended		Six Months Ended
	June 30, 2022
	(in thousands)
Long-lived assets impairments and write-offs	$	—	$	12,653
Severance and employee-related costs		2,396		9,412
Exit and other related costs		6,000		8,993
Total	$	8,396	$	31,058

Schedule of Activity Related to Restructuring Liabilities Associated to Restructuring Initiatives

The following table summarizes the activity related to the restructuring liabilities associated with our restructuring initiatives for the six months ended June 30, 2022:

	Three Months Ended			Six Months Ended
	June 30, 2022
	(in thousands)
Beginning balance	$	7,155		$	—
Reclassification of final payment obligation related to a manufacturing   agreement that was recognized in the prior period (see Note 13)		—			2,185
Restructuring, impairment and related charges		8,396			31,058
Cash payments		(4,328	)		(8,195	)
Noncash activities		—			(13,825	)
Ending balance	$	11,223		$	11,223
Reported as of June 30, 2022				(in thousands)
Accrued compensation and benefits					2,223
Accrued research and development liabilities					6,000
Other accrued liabilities					3,000
				$	11,223