X0306 4 2020-01-21 0 0001735438 MeiraGTx Holdings plc MGTX 0001742734 Giroux Richard 430 E. 29TH STREET, 10TH FLOOR NEW YORK NY 10016 0 1 0 0 CFO & COO Ordinary Shares 2019-12-27 5 G 0 E 1000 0.00 D 1185868 D Ordinary Shares 2020-01-21 4 S 0 8498 19.51 D 1177370 D Ordinary Shares 2020-01-21 4 S 0 502 20.32 D 1176868 D Ordinary Shares 2020-01-22 4 S 0 9000 19.34 D 1167868 D Ordinary Shares 5152 I By Spouse The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 11, 2019. The price reported reflects the weighted average sales price. The shares were sold in multiple transactions at prices ranging from $19.07 to $20.05, inclusive. The reporting person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price. The price reported reflects the weighted average sales price. The shares were sold in multiple transactions at prices ranging from $20.07 to $20.42, inclusive. The price reported reflects the weighted average sales price. The shares were sold in multiple transactions at prices ranging from $18.83 to $19.80, inclusive. /s/ Richard Giroux 2020-01-23