Statement of Stockholders’ Equity - USD ($) shares in Thousands, $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Common stock, beginning balance (in shares) at Dec. 31, 2021		55,703
Beginning balance at Dec. 31, 2021	$ 345,097	$ 56	$ 608,064	$ (39)	$ (262,984)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon vesting and exercise of options and vesting of restricted stock (in shares)		1,003
Issuance of common stock upon vesting and exercise of options and vesting of restricted stock	1,834	$ 1	1,833
Stock-based compensation expense	31,145		31,145
Employee stock purchase plan (in shares)		261
Employee stock purchase plan	380		380
Net unrealized gain (loss) on available-for-sale securities	(753)			(753)
Net loss	$ (133,204)				(133,204)
Common stock, ending balance (in shares) at Dec. 31, 2022	56,967	56,967
Beginning balance at Dec. 31, 2022	$ 244,499	$ 57	641,422	(792)	(396,188)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon vesting and exercise of options and vesting of restricted stock (in shares)		1,553
Issuance of common stock upon vesting and exercise of options and vesting of restricted stock	921	$ 2	919
Stock-based compensation expense	24,982		24,982
Employee stock purchase plan (in shares)		426
Employee stock purchase plan	538		538
Net unrealized gain (loss) on available-for-sale securities	811			811
Net loss	$ (112,673)				(112,673)
Common stock, ending balance (in shares) at Dec. 31, 2023	58,946	58,946
Beginning balance at Dec. 31, 2023	$ 159,078	$ 59	$ 667,861	$ 19	$ (508,861)