X0306 4 2021-03-07 0 0001741830 Kronos Bio, Inc. KRON 0001221355 Kazam Joshua A C/O KRONOS BIO, INC. 1300 SO. EL CAMINO REAL, SUITE 400 SAN MATEO CA 94402 1 0 0 0 Common Stock 2022-03-07 5 G 0 E 211000 0.00 A 305481 D Common Stock 2022-03-07 5 G 0 E 211000 0.00 D 94481 D 68,815 of the shares are held jointly with spouse. On March 7, 2022, the reporting person transferred 211,000 shares of common stock to an irrevocable grantor trust having an independent trustee. The reporting person disclaims beneficial ownership of these shares except to the extent, if any, of the reporting person's pecuniary interest therein. /s/ Allison Frisbee, Attorney-in-Fact 2022-03-09