<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2020-11-02</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001690585</issuerCik>
        <issuerName>Magenta Therapeutics, Inc.</issuerName>
        <issuerTradingSymbol>MGTA</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001741389</rptOwnerCik>
            <rptOwnerName>Mahoney Stephen F.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O MAGENTA THERAPEUTICS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>100 TECHNOLOGY SQUARE</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02139</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <footnotes></footnotes>

    <remarks>Chief Financial and Operating Officer

Exhibit 24.1:  Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Zoran Zdraveski, Attorney-in-Fact for Stephen F. Mahoney</signatureName>
        <signatureDate>2020-11-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
