EXHIBIT 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in the following Registration Statements:

(1) Registration Statement (Form S-3 No. 333-236193),

(2) Registration Statement (Form S-3 No. 333-260529)

(3) Registration Statement (Form S-8 No. 333-228045); and

(4) Registration Statement (Form S-8 No. 333-261128);

of our report dated March 30, 2022, with respect to the consolidated financial statements of RVL Pharmaceuticals plc included in this Annual Report (Form 10-K) of RVL Pharmaceuticals plc for the year ended December 31, 2021.

/s/Ernst & Young LLP

Iselin, New Jersey

March 30, 2022