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INCOME TAXES (Tables)
12 Months Ended
Dec. 31, 2025
Income Tax Disclosure [Abstract]  
Schedule of Income (Loss) Before Income Taxes
The following table summarizes income (loss) before income taxes:
(in thousands)2025
Domestic$(8,978)
Foreign— 
Total$(8,978)
Schedule of Effective Income Tax Rates
The following is a reconciliation from the Company's statutory rate to the effective tax rate reported in the financial statements:
2025
(in thousands)AmountRate
Statutory federal income tax rate$(1,885)21.0%
Tax credits (federal):
Orphan drug credit(1,331)14.8 %
Other(231)2.6 %
Valuation allowance2,203 (24.5)%
Non-deductible or non-taxable items:
Share-based compensation1,227 (13.7)%
Other adjustments17 (0.2%)
Effective income tax rate$— 0.0%
The Company’s effective income tax rates are different from the federal statutory tax rates in 2024 predominantly due to the valuation allowance, tax credits, and state taxes. A reconciliation of the effect of applying the federal statutory rate to the net loss and effective income tax rate are as follows:
2024
U.S. federal statutory income tax rate21.0%
State income taxes, net of federal income tax benefit5.4%
Tax credits10.7%
Other(2.9)%
Valuation allowance(34.2)%
Effective income tax rate0.0%
Schedule of Deferred Income Tax Benefits and Liabilities
The tax effect of temporary differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases that give rise to deferred tax assets and liabilities are as follows at December 31, 2025 and 2024:
(in thousands)20252024
Net operating loss carryforwards$50,322 $45,973 
Amortization1,775 1,341 
Section 174 capitalization19,947 22,479 
Research and development tax credits25,701 24,047 
Share-based compensation2,405 2,654 
Other301 1,476 
Total deferred tax assets100,451 97,970 
Valuation allowance(100,451)(97,970)
Net deferred tax assets$— $—