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STOCKHOLDERS' EQUITY (Tables)
 12 Months Ended
Dec. 31, 2025
Equity [Abstract]  
Schedule of Share-based Compensation
Share-based compensation is comprised of the Company's stock options, restricted stock awards, restricted stock units and shares issued pursuant to the employee stock purchase plan, and is classified in the consolidated statements of operations and comprehensive loss for the years ended December 31, 2025 and 2024 and was as follows:
FOR THE YEAR ENDED
DECEMBER 31,
(in thousands)20252024
Research and development$2,250 $3,269 
General and administrative3,064 4,724 
$5,314 $7,993 
Schedule of Stock Option Activity
The following table summarizes stock option activity for the year ended December 31, 2025:
Stock OptionsNumber of Option Shares Weighted-Average Exercise PriceWeighted-Average Contractual Term
(in years)		Aggregate Intrinsic Value
(in thousands)
Outstanding stock options at December 31, 2024529,342$62.83 7.8$— 
Granted224,179$5.87 
Forfeited(51,758)$32.54 
Expired(73,483)$76.34 
Exercised—$— 
Outstanding at December 31, 2025628,280$43.42 7.6$89 
Exercisable stock options at December 31, 2025399,047$58.72 7.1$— 
Schedule of Assumptions of Fair Value of Option Pricing Granted
The fair value of the stock options granted during the years ended December 31, 2025 and 2024 was determined using the Black-Scholes option pricing model with the following assumptions:
FOR THE YEAR ENDED DECEMBER 31,
20252024
Expected volatility
91.88% - 119.61%
89.41% - 94.48%
Expected term (years)
5.27 - 6.02
5.50 - 6.02
Risk free interest rate
4.03% - 4.39%
3.93% - 4.35%
Expected dividend yield— — 
Exercise price
$2.38 - $7.60
$14.88 - $19.20
Schedule of Nonvested Restricted Common Stock Awards
A summary of the status of the Company's nonvested restricted common stock awards at December 31, 2025 and changes during the year ended December 31, 2025 was as follows:
Restricted Stock AwardsShares Weighted-Average Grant Date Fair Value Per Share
Nonvested restricted common stock awards at December 31, 20242,687$31.76 
Granted—$— 
Vested(2,687)$31.76 
Forfeited—$— 
Nonvested restricted common stock awards at December 31, 2025—$— 
Schedule of Nonvested Restricted Common Stock Units
A summary of the status of the Company's nonvested restricted common stock units at December 31, 2025 and changes during the year ended December 31, 2025 was as follows:
Restricted Stock UnitsShares Weighted-Average Grant Date Fair Value Per Share
Nonvested restricted common stock units at December 31, 2024133,069$18.89 
Granted59,500$5.96 
Forfeited(66,646)$12.34 
Vested(87,320)$19.18 
Nonvested restricted common stock units at December 31, 202538,603$9.60