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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Cash Flows from Operating Activities:    
Net loss $ (66,654) $ (47,013)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 167 109
Net accretion of discounts/premiums on debt securities (435) 0
Stock-based compensation 9,499 3,645
Loss on investment in joint venture 1,075 1,505
Changes in operating assets and liabilities:    
Prepaid expenses, right-of-use assets and other assets (4,645) (4,507)
Accounts payable 487 (976)
Accrued expenses and operating lease liabilities 3,222 1,704
Net cash used in operating activities (57,284) (45,533)
Cash Flows used in Investing Activities:    
Purchases of marketable securities 201,316 0
Proceeds from maturities of marketable securities 89,500 0
Purchase of property and equipment (54) (333)
Investment in joint venture (300) (2,000)
Net cash used in investing activities (112,170) (2,333)
Cash Flows from Financing Activities:    
Proceeds from the issuance of common stock and pre-funded warrants upon the completion of the follow-on offering, net of underwriting discounts and commissions of $3,289 51,533 0
Proceeds from the issuance of common stock upon completion of the initial public offering, net of underwriting discounts and commissions of $6,488 0 86,200
Proceeds from the issuance of common stock from the stock purchase plan 217 0
Proceeds from the issuance of common stock from exercise of stock options 21 0
Payments of offering costs (693) (3,233)
Net cash provided by financing activities 51,078 82,967
Net increase (decrease) in cash and cash equivalents (118,376) 35,101
Cash and cash equivalents - beginning of year 175,334 140,233
Cash and cash equivalents - end of year 56,958 175,334
Supplemental Disclosures of Noncash Investing and Financing Activities:    
Offering costs in accounts payable and accrued expenses 139 0
Property and equipment in accounts payable and accrued expenses $ 0 $ 13