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Acquisitions, Divestitures and Other Arrangements - Narrative (Details)
$ / shares in Units, $ in Millions
3 Months Ended 9 Months Ended
Aug. 27, 2021
USD ($)
$ / shares
Aug. 01, 2021
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2022
USD ($)
Sep. 30, 2021
USD ($)
Jun. 09, 2022
USD ($)
Feb. 01, 2022
USD ($)
Dec. 31, 2021
USD ($)
employee
May 05, 2021
USD ($)
Business Acquisition [Line Items]                  
Contract with customer, asset, before allowance for credit loss             $ 55    
Proceeds from site divestitures       $ 11 $ 0        
Liabilities     $ 8,203 8,203       $ 8,945  
Variable Interest Entity, Primary Beneficiary | BexCaFe, LLC                  
Business Acquisition [Line Items]                  
Liabilities           $ 59      
Payment on agreement     10            
Variable Interest Entity, Primary Beneficiary | BexCaFe, LLC | Future Milestone Payments And Sales Royalties                  
Business Acquisition [Line Items]                  
Liabilities           49      
Intangible assets, primarily acquired in-process research and development (IPR&D) | Variable Interest Entity, Primary Beneficiary | BexCaFe, LLC                  
Business Acquisition [Line Items]                  
Finite-lived intangible assets           $ 59      
Disposal Group, Held-for-sale or Disposed of by Sale, Not Discontinued Operations                  
Business Acquisition [Line Items]                  
Number of employees transferred | employee               600  
Disposal Group, Held-for-sale or Disposed of by Sale, Not Discontinued Operations | Microbiome R&D Platform Carve-Out                  
Business Acquisition [Line Items]                  
Gain on disposal       3          
Disposal Group, Held-for-sale or Disposed of by Sale, Not Discontinued Operations | Shawnee                  
Business Acquisition [Line Items]                  
Cash received in agreement to divest   $ 78              
Duration over which proceeds will be received   3 years              
Proceeds from site divestitures     $ 11 $ 11          
KindredBio                  
Business Acquisition [Line Items]                  
Common stock price (usd per share) | $ / shares $ 9.25                
Cash paid in acquisition $ 444                
Settlement of liability related to previous license agreement                 $ 29