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Acquisitions, Divestitures and Other Arrangements - Narrative (Details)
$ / shares in Units, $ in Millions
3 Months Ended 6 Months Ended
Feb. 01, 2022
USD ($)
Aug. 27, 2021
USD ($)
$ / shares
Aug. 01, 2021
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2022
USD ($)
Jun. 09, 2022
USD ($)
Dec. 31, 2021
USD ($)
employee
May 05, 2021
USD ($)
Business Acquisition [Line Items]                
Contract with customer, asset, before allowance for credit loss $ 55              
Liabilities       $ 8,461 $ 8,461   $ 8,945  
Variable Interest Entity, Primary Beneficiary | BexCaFe, LLC                
Business Acquisition [Line Items]                
Liabilities           $ 59    
Variable Interest Entity, Primary Beneficiary | BexCaFe, LLC | Future Milestone Payments And Sales Royalties                
Business Acquisition [Line Items]                
Liabilities           49    
Intangible assets, primarily acquired in-process research and development (IPR&D) | Variable Interest Entity, Primary Beneficiary | BexCaFe, LLC                
Business Acquisition [Line Items]                
Finite-lived intangible assets           $ 59    
Speke                
Business Acquisition [Line Items]                
Period after which proceeds will be received 12 months              
Disposal Group, Held-for-sale or Disposed of by Sale, Not Discontinued Operations                
Business Acquisition [Line Items]                
Number of employees transferred | employee             600  
Disposal Group, Held-for-sale or Disposed of by Sale, Not Discontinued Operations | Microbiome R&D Platform Carve-Out                
Business Acquisition [Line Items]                
Gain on disposal       $ 3 $ 3      
Disposal Group, Held-for-sale or Disposed of by Sale, Not Discontinued Operations | Shawnee                
Business Acquisition [Line Items]                
Proceeds from product divestitures     $ 51          
Duration over which proceeds will be received     3 years          
Disposal Group, Held-for-sale or Disposed of by Sale, Not Discontinued Operations | Speke                
Business Acquisition [Line Items]                
Proceeds from product divestitures $ 29              
Duration over which proceeds will be received 1 year              
KindredBio                
Business Acquisition [Line Items]                
Common stock price (in dollars per share) | $ / shares   $ 9.25            
Cash paid in acquisition   $ 444            
Settlement of liability related to previous license agreement               $ 29