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Related Parties and Related-Party Transactions - Additional Information (Detail) - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Dec. 31, 2019
Dec. 31, 2018
Related Party Transaction [Line Items]            
Research and development expense $ 3,670,000 $ 5,979,000 $ 10,498,000 $ 19,146,000 $ 22,449,000 $ 27,095,000
Adimab, LLC | Collaboration Agreement            
Related Party Transaction [Line Items]            
Research and development expense     0 1,500,000 1,500,000 0
StackWave, LLC | Software License and Services Agreement            
Related Party Transaction [Line Items]            
Research and development expense     17,000   20,000 37,000
Capitalized software $ 200,000 $ 700,000 $ 200,000 $ 700,000 $ 100,000 $ 300,000