Note 14 - Income Taxe (Tables)

12 Months Ended

Dec. 31, 2025

Notes Tables

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

	December 31,
	2025					2024
Federal statutory rate	$	(13,963	)	21.0	%	$	(10,368	)	21.0	%
Adjustment resulting from the tax effect of:
State and local income tax, net of federal (national) income tax effect		(4,416	)	6.6	%		(3,454	)	7.0	%
Foreign Tax Effects		-		0.0	%		-		0.0	%
Effect of changes in tax laws or rates enacted in the current period		-		0.0	%		-		0.0	%
Effect of cross-border tax laws		-		0.0	%		-		0.0	%
Tax Credits
Research and development tax credits		(2,045	)	3.1	%		(2,864	)	5.8	%
Changes in valuation allowance		19,744		-29.8	%		15,778		-32.0	%
Nontaxable or nondeductible items
Stock compensation & other nondeductible expenses		680		-0.9	%		532		-1.1	%
Changes in unrecognized tax benefits		-		0.0	%		-		0.0	%
Other		-		0.0	%		376		-0.7	%
Effective income tax rate	$	-		0.0	%	$	-		0.0	%

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

	December 31,
	2025			2024
Deferred tax assets	(000's)
Federal net operating loss carryforwards	$	42,075		$	16,775
State net operating loss carryforwards		13,063			5,063
Research and development credits		11,297			9,252
Section 174 Capitalization		6,015			22,724
Share-based compensation		5,001			3,922
Lease liabilities		2,685			1,812
Capitalized licensing fees		1,266			1,375
Other		406			494
Subtotal		81,808			61,417
Less valuation allowance		(79,245	)		(59,521	)
Deferred tax assets, net of valuation allowance		2,563			1,896
Deferred tax liabilities
Right-of-use assets		(2,486	)		(1,839	)
Other		(77	)		(57	)
Net deferred tax assets	$	—		$	—