Note 15 - Income Taxes (Tables)

12 Months Ended

Dec. 31, 2022

Notes Tables

Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]

	December 31,
	2022			2021
Statutory rate		21.0	%		21.0	%
State taxes		5.6	%		2.1	%
Share-based compensation & other nondeductible expenses		-2.7	%		-1.0	%
Write-off of in-process R&D		0.0	%		-12.9	%
Research credits		1.4	%		0.8	%
Other		-0.1	%		0.0	%
Change in valuation allowance		-25.2	%		-10.0	%
Total		0.0	%		0.0	%

Schedule of Deferred Tax Assets and Liabilities [Table Text Block]

	December 31,
	2022			2021
Deferred tax assets	(000's)
Federal net operating loss carryforwards	$	12,405		$	10,847
State net operating loss carryforwards		2,687			2,228
Research and development credits		3,273			2,716
Section 174 Capitalization		7,294			—
Share-based compensation		701			706
Lease liabilities		801			1,131
Capitalized licensing fees		1,591			1,637
Other		70			22
Subtotal		28,822			19,287
Less valuation allowance		(28,013	)		(18,113	)
Deferred tax assets, net of valuation allowance		809			1,174
Deferred tax liabilities
Right-of-use assets		(809	)		(1,116	)
Other		—			(58	)
Net deferred tax assets	$	—		$	—