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Note 8 - Stock-based Compensation - Summary of Stock Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
6 Months Ended 12 Months Ended
Jun. 30, 2022
Dec. 31, 2021
Jun. 30, 2021
Outstanding (in shares) 3,659    
Outstanding, weighted average exercise price per share (in dollars per share) $ 4.99    
Outstanding, weighted average remaining contractual term (Year) 8 years 11 months 8 days 8 years 8 months 1 day  
Granted (in shares) 2,229    
Granted, weighted average exercise price per share (in dollars per share) $ 2.29    
Granted, weighted average remaining contractual term (Year) 9 years 6 months 10 days    
Exercised (in shares) 0    
Exercised (in dollars per share)    
Forfeited/cancelled (in shares) (244)    
Forfeited/cancelled, weighted average exercise price per share (in dollars per share) $ 4.06    
Outstanding (in shares) 5,644 3,659  
Outstanding, weighted average exercise price per share (in dollars per share) $ 3.97 $ 4.99  
Outstanding, aggregate intrinsic value $ 839    
Vested (in shares) 2,182    
Vested, weighted average exercise price per share (in dollars per share) $ 4.86    
Vested, weighted average remaining contractual term (Year) 9 years 3 months 14 days    
Vested, aggregate intrinsic value $ 47   $ 0