License, Research and Collaboration Agreements - Additional Information (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Abl Bio Agreement Member
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Milestone Payments Received	$ 5,000
Milestone payments	6,000
Abl Bio Agreement Member | Oncology Member
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Research and development milestone payments	110,000
Commercial milestone payments	295
Abl Bio Agreement Member | Ophthalmology Member
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Milestone Payment And Royalties Received	$ 185,000
Adimab Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Research and development milestone payments			$ 1,500
Collaboration agreement date	Oct. 16, 2014
Milestone payments	$ 0
Future Milestone Payments	2,000
Future milestone payments	2,000
FUJIFILM Diosynth Biotechnologies Agreement
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Future Milestone Payments	1,200
Future milestone payments	1,200
Cash payment for license agreement	1,200	$ 2,600
Research and development	1,000	$ 900
Total expense to be recognized	$ 2,900