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Document and Entity Information - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Feb. 28, 2022
Jun. 30, 2021
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2021    
Document Fiscal Year Focus 2021    
Document Fiscal Period Focus FY    
Entity Registrant Name Compass Therapeutics, Inc.    
Entity Central Index Key 0001738021    
Current Fiscal Year End Date --12-31    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company true    
Entity Ex Transition Period false    
ICFR Auditor Attestation Flag false    
Entity Common Stock, Shares Outstanding   101,302,594  
Entity Public Float     $ 180
Entity Shell Company false    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers Yes    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity File Number 000-55939    
Entity Tax Identification Number 82-4876496    
Entity Address, Address Line One 80 Guest Street    
Entity Address, Address Line Two Suite 601    
Entity Address, City or Town Boston    
Entity Address, State or Province MA    
Entity Address, Postal Zip Code 02135    
City Area Code 617    
Local Phone Number 500-8099    
Entity Incorporation, State or Country Code DE    
Document Annual Report true    
Document Transition Report false    
Title of each class Common Stock, $0.0001 par value per share    
Trading Symbol CMPX    
Security Exchange Name NASDAQ    
Documents Incorporated by Reference

DOCUMENTS INCORPORATED BY REFERENCE

The registrant intends to file a definitive proxy statement pursuant to Regulation 14A relating to the 2022 Annual Meeting of Stockholders within 120 days of the end of the registrant’s fiscal year ended December 31, 2021. Portions of such definitive proxy statement are incorporated by reference into Part III of this Annual Report on Form 10-K to the extent stated herein.

   
Auditor Firm ID 596    
Auditor Name CohnReznick LLP    
Auditor Location Melville, NY U.S.A