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License, Research and Collaboration Agreements - Additional Information (Details)
3 Months Ended 9 Months Ended
Sep. 30, 2021
USD ($)
Sep. 30, 2021
USD ($)
ABL Bio Corporation Agreements    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Upfront payment received   $ 5,000,000
ABL Bio Corporation Agreements | Oncology    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Eligible to receive development milestone payments   110,000,000
Eligible to receive commercial milestone payments   295,000,000
ABL Bio Corporation Agreements | Ophthalmology    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Milestone payment and royalties received   $ 185,000,000
Adimab Agreement    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Collaboration agreement date   Oct. 16, 2014
Milestone payments   $ 0
Future milestone payments $ 2,000,000.0 2,000,000.0
FUJIFILM Diosynth Biotechnologies ("Fujifilm") Agreement    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]    
Future milestone payments 1,200,000 1,200,000
Prepayments for future work   1,800,000
Total expense to be recognized   3,000,000.0
Cash payment for license agreement 100,000 1,300,000
Research and development $ 25,000 $ 1,000,000.0