X0609 4 2026-06-01 1 0001737953 Replimune Group, Inc. REPL 0001986597 Sarchi Christopher false C/O REPLIMUNE GROUP, INC. 500 UNICORN PARK DRIVE, SUITE 303 WOBURN MA 01801 0 1 0 0 Chief Commercial Officer 1 Common Stock 2026-06-01 4 S 0 12000 9.24 D 180962 D The sales reported on this Form 4 were made by the Reporting Person pursuant to a trading plan adopted on December 15, 2025, that is intended to comply with Rule 10b5-1(c) under the Securities Exchange Act of 1934, as amended. The price reported reflects a weighted average price of the Shares. The Shares were sold in multiple transactions at prices ranging from $9.15 to $9.62 per Share. The Reporting Person will provide to the Issuer, any security holder of the Issuer or the Securities Exchange Commission staff, upon request, information regarding the number of Shares sold at each price within the range. /s/ Shawn Glidden, attorney-in-fact 2026-06-03