X0306 4 2022-05-31 0 0001737927 Canopy Growth Corp CGC 0001553612 Klein David Eric C/O CANOPY GROWTH CORPORATION 1 HERSHEY DRIVE SMITHS FALLS A6 K7A 0A8 ONTARIO, CANADA 1 1 0 0 Chief Executive Officer COMMON SHARES 2022-05-31 4 F 0 85976 6.3712 D 192077 D Represents deemed disposition of shares of common shares to the Issuer to satisfy tax withholding obligations in connection with vesting of restricted stock units. Prices are expressed in Canadian dollars. Includes 646 common shares acquired under the Canopy Growth Corporation Employee Stock Purchase Plan, on February 11, 2022 /s/ Emily Evelyn Howe for David Eric Klein 2022-06-02