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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Operating expenses:        
Research and development $ 47,296,000 $ 31,774,000 $ 89,337,000 $ 55,177,000
General and administrative 15,862,000 14,187,000 31,502,000 27,245,000
Total operating expenses 63,158,000 45,961,000 120,839,000 82,422,000
Loss from operations (63,158,000) (45,961,000) (120,839,000) (82,422,000)
Other income (expense), net:        
Interest and other income, net 2,340,000 4,559,000 5,600,000 9,384,000
Other expenses (156,000) 0 (215,000) 0
Total other income (expense), net 2,184,000 4,559,000 5,385,000 9,384,000
Loss before income taxes (60,974,000) (41,402,000) (115,454,000) (73,038,000)
Benefit from income taxes 0 159,000 0 209,000
Net loss (60,974,000) (41,243,000) (115,454,000) (72,829,000)
Other comprehensive income:        
Net unrealized gain on available-for-sale investments 220,000 756,000 685,000 1,855,000
Net comprehensive loss $ (60,754,000) $ (40,487,000) $ (114,769,000) $ (70,974,000)
Net loss per share, basic and diluted (in dollars per share) $ (0.53) $ (0.41) $ (1.03) $ (0.74)
Weighted-average number of shares used in computing net loss per share, basic and diluted (in shares) 115,377,210 99,846,946 112,163,123 98,588,410