X0306 4 2019-09-03 0 0001609550 Inspire Medical Systems, Inc. INSP 0001737136 Herbert Timothy P. C/O INSPIRE MEDICAL SYSTEMS, INC. 5500 WAYZATA BLVD., SUITE 1600 GOLDEN VALLEY MN 55416 1 1 0 0 CEO and President Common Stock 2019-09-03 4 S 0 5499 66.56 D 94125 I By family trust Common Stock 2019-09-03 4 S 0 2472 67.44 D 91653 I By family trust Common Stock 2019-09-03 4 S 0 1846 68.48 D 89807 I By family trust Common Stock 2019-09-03 4 S 0 183 69.65 D 89624 I By family trust Common Stock 350 I By daughter Common Stock 282875 I By family trust The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $66.04 to $67.03. The reporting person undertakes to provide Inspire Medical Systems, Inc. (the "Company"), any security holder of the Company, or the staff of the Securities and Exchange Commission (the "SEC"), upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Shares held by the Timothy P. Herbert 2013 Family Irrevocable GST Trust U/A/D November 27, 2013. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $67.05 to $68.01. The reporting person undertakes to provide the Company, any security holder of the Company, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $68.17 to $68.95. The reporting person undertakes to provide the Company, any security holder of the Company, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $69.64 to $69.66. The reporting person undertakes to provide the Company, any security holder of the Company, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. Shares held by the Margaret C. Herbert 2018 Family Irrevocable GST Trust. /s/ Richard Buchholz, Attorney-in-Fact for Timothy P. Herbert 2019-09-05