SCHEDULE 13G/A 0001930214 XXXXXXXX LIVE 1 Common Stock, par value $0.0001 per share 12/31/2025 0001736730 Camp4 Therapeutics Corp 13463J101 One Kendall Square Building 1400 West, 3rd Floor Cambridge MA 02139 Rule 13d-1(c) Vivo Opportunity Fund Holdings, L.P. b DE 3856991.00 0.00 3856991.00 0.00 3856991.00 N 7.4 PN The number represents shares of common stock, $0.0001 par value (the "Common Stock") of CAMP4 Therapeutics Corporation (the "Issuer") held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P. The percentage is based on 51,880,185 shares of Common Stock of the Issuer outstanding as of December 18, 2025, as disclosed in the prospectus supplement filed by the Issuer on December 18, 2025 with the Securities and Exchange Commission ("SEC") pursuant to Rule 424(b)(5), which forms part of the Issuer's Registration Statement on Form S-3 (File No. 333-291432). Vivo Opportunity, LLC b DE 3856991.00 0.00 3856991.00 0.00 3856991.00 N 7.4 OO The number represents shares of Common Stock of the Issuer held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P. The percentage is based on 51,880,185 shares of Common Stock of the Issuer outstanding as of December 18, 2025, as disclosed in the prospectus supplement filed by the Issuer on December 18, 2025 with the SEC pursuant to Rule 424(b)(5), which forms part of the Issuer's Registration Statement on Form S-3 (File No. 333-291432). Vivo Opportunity Cayman Fund, L.P. b E9 389577.00 0.00 389577.00 0.00 389577.00 N 0.8 PN The number represents shares of Common Stock of the Issuer held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P. The percentage is based on 51,880,185 shares of Common Stock of the Issuer outstanding as of December 18, 2025, as disclosed in the prospectus supplement filed by the Issuer on December 18, 2025 with the SEC pursuant to Rule 424(b)(5), which forms part of the Issuer's Registration Statement on Form S-3 (File No. 333-291432). Vivo Opportunity Cayman, LLC b E9 389577.00 0.00 389577.00 0.00 389577.00 N 0.8 OO The number represents shares of Common Stock of the Issuer held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P. The percentage is based on 51,880,185 shares of Common Stock of the Issuer outstanding as of December 18, 2025, as disclosed in the prospectus supplement filed by the Issuer on December 18, 2025 with the SEC pursuant to Rule 424(b)(5), which forms part of the Issuer's Registration Statement on Form S-3 (File No. 333-291432). Camp4 Therapeutics Corp One Kendall Square Building 1400 West, 3rd Floor Cambridge, MA 02139 Vivo Opportunity Fund Holdings, L.P. and its General Partner Vivo Opportunity, LLC Vivo Opportunity Cayman Fund, L.P. and its General Partner Vivo Opportunity Cayman, LLC 192 Lytton Avenue, Palo Alto, CA 94301 Vivo Opportunity Fund Holdings, L.P. is a Delaware limited partnership. Vivo Opportunity, LLC is a Delaware limited liability company. Vivo Opportunity Cayman Fund, L.P. is a Cayman Islands limited partnership. Vivo Opportunity Cayman, LLC is a Cayman Islands limited liability company. Y Vivo Opportunity, LLC beneficially owns 3,856,991 shares of Common Stock. The securities are held of record by Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity, LLC is the general partner of Vivo Opportunity Fund Holdings, L.P. Vivo Opportunity Cayman, LLC beneficially owns 389,577 shares of Common Stock. The securities are held of record by Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Cayman, LLC is the general partner of Vivo Opportunity Cayman Fund, L.P. Vivo Opportunity Fund Holdings, L.P.: 7.4% Vivo Opportunity, LLC: 7.4% Vivo Opportunity Cayman Fund, L.P.: 0.8% Vivo Opportunity Cayman, LLC.: 0.8% Vivo Opportunity Fund Holdings, L.P.: 3,856,991 shares Vivo Opportunity, LLC: 3,856,991 shares Vivo Opportunity Cayman Fund, L.P.: 389,577 shares Vivo Opportunity Cayman, LLC: 389,577 shares 0 Vivo Opportunity Fund Holdings, L.P.: 3,856,991 shares Vivo Opportunity, LLC: 3,856,991 shares Vivo Opportunity Cayman Fund, L.P.: 389,577 shares Vivo Opportunity Cayman, LLC: 389,577 shares 0 Y Y Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Vivo Opportunity Fund Holdings, L.P. /s/ Kevin Dai 02/13/2026 Vivo Opportunity, LLC /s/ Kevin Dai 02/13/2026 Vivo Opportunity Cayman Fund, L.P. /s/ Kevin Dai 02/13/2026 Vivo Opportunity Cayman, LLC /s/ Kevin Dai 02/13/2026