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Related-Party Transactions - Collaboration and License Agreements (Details) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jan. 30, 2019
Oct. 16, 2018
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Dec. 31, 2019
Feb. 27, 2019
Related Party Transaction [Line Items]                
Shares issued to related party     37,362,416   37,362,416   36,791,906  
Private Placement [Member]                
Related Party Transaction [Line Items]                
Shares issued to related party               5,797,102
Clinical IRD Product Candidate development | Maximum [Member]                
Related Party Transaction [Line Items]                
Additional development and commercialization milestones $ 340,000,000.0              
Clinical IRD Product Candidate development | Collaboration Agreement [Member]                
Related Party Transaction [Line Items]                
Royalties receivable, as a percentage 20.00%              
JJDC | Private Placement [Member]                
Related Party Transaction [Line Items]                
Shares issued to related party               2,898,550
Janssen Pharmaceuticals Inc [Member] | Collaboration Agreement [Member]                
Related Party Transaction [Line Items]                
Non-refundable upfront fee received $ 100,000,000         $ 100,000,000.0    
Deferred revenue - related party recognized as license revenue     $ 2,473,705 $ 1,981,676 $ 6,683,281 2,766,636 $ 13,291,956  
Reimbursement of research and development expenses     10,574,561 2,952,121 24,604,578 $ 3,989,663    
Revenue, remaining performance obligation, amount     73,694,653   73,694,653      
Estimated period to recognize remaining deferred revenue           4 years 9 months    
Deferred revenue - related party     73,694,653   73,694,653   $ 86,214,091  
Janssen Pharmaceuticals Inc [Member] | Research, development and commercialization of gene therapies | Collaboration Agreement [Member]                
Related Party Transaction [Line Items]                
Non-refundable upfront fee received $ 100,000,000.0              
Janssen Pharmaceuticals Inc [Member] | Clinical IRD Product Candidate development | Collaboration Agreement [Member]                
Related Party Transaction [Line Items]                
Percentage of clinical and commercialization costs to be paid by related party 100.00%              
Janssen Pharmaceuticals Inc [Member] | Research IRD Candidates development | Collaboration Agreement [Member]                
Related Party Transaction [Line Items]                
Percentage of clinical and commercialization costs to be paid by related party 100.00%              
Janssen Pharmaceuticals Inc [Member] | Riboswitch Research | Collaboration Agreement [Member]                
Related Party Transaction [Line Items]                
Deferred revenue - related party   $ 658,667            
Deferred research funding, amortization period   8 months            
Janssen Pharmaceuticals Inc [Member] | Riboswitch Research | Collaboration Agreement [Member] | Research and Development Expenses [Member]                
Related Party Transaction [Line Items]                
Amortization of deferred revenue - related party     $ 0 $ 192,076 $ 0 $ 444,399