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CONDENSED CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY - USD ($)
Ordinary Shares [Member]
Private Placement [Member]
Ordinary Shares [Member]
License Agreement [Member]
Ordinary Shares [Member]
Capital in Excess of Par Value [Member]
Private Placement [Member]
Capital in Excess of Par Value [Member]
License Agreement [Member]
Capital in Excess of Par Value [Member]
Accumulated Other Comprehensive (Loss) Income [Member]
Accumulated Deficit [Member]
Private Placement [Member]
License Agreement [Member]
Total
Beginning Balance at Dec. 31, 2018     $ 1,064     $ 229,054,460 $ 293,666 $ (148,289,717)     $ 81,059,473
Beginning Balance, Shares at Dec. 31, 2018     27,386,632                
Issuance of ordinary shares in connection with a license agreement   $ 6     $ 1,966,334         $ 1,966,340  
Issuance of ordinary shares in connection with a license agreement, shares   158,832                  
Sale of ordinary shares in connection with private placement, net of issuance costs of $2,426,953 $ 225     $ 77,572,822         $ 77,573,047    
Sale of ordinary shares in connection with private placement, net of issuance costs, shares 5,797,102                    
Share-based compensation           2,934,991         2,934,991
Foreign currency translation             (1,133,683)       (1,133,683)
Net loss               (17,981,918)     (17,981,918)
Balance at Mar. 31, 2019     $ 1,295     311,528,607 (840,017) (166,271,635)     144,418,250
Balance, Shares at Mar. 31, 2019     33,342,566                
Beginning Balance at Dec. 31, 2018     $ 1,064     229,054,460 293,666 (148,289,717)     $ 81,059,473
Beginning Balance, Shares at Dec. 31, 2018     27,386,632                
Exercised stock options, shares                     134,533
Balance at Dec. 31, 2019     $ 1,429     395,630,666 (1,794,042) (203,035,952)     $ 190,802,101
Balance, Shares at Dec. 31, 2019     36,791,906                
Exercised stock options     $ 1     175,076         $ 175,077
Exercised stock options, shares     26,010               26,010
Share-based compensation           5,682,881         $ 5,682,881
Foreign currency translation             3,945,924       3,945,924
Net loss               (15,681,197)     (15,681,197)
Balance at Mar. 31, 2020     $ 1,430     $ 401,488,623 $ 2,151,882 $ (218,717,149)     $ 184,924,786
Balance, Shares at Mar. 31, 2020     36,817,916