144 0001678604 XXXXXXXX LIVE 0001735438 MEIRAGTX HOLDINGS PLC 001-38520 450 EAST 29TH STREET 14TH FLOOR NEW YORK NY 10016 646-860-7985 Alexandria Forbes Officer Director Ordinary Shares Merrill Lynch

200 Park Avenue New York NY 10166

47500 378575 80365359 07/08/2025 NASDAQ Ordinary Shares 03/02/2018 Incentive Compensation Stock Grant Issuer N 35625 03/02/2018 N/A Ordinary Shares 06/07/2018 Incentive Compensation Stock Grant Issuer N 11875 06/07/2018 N/A Y 07/08/2025 08/21/2024 /s/ Alexandria Forbes