CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Cash flows from operating activities:
Net loss	$ (82,865,874)	$ (31,044,535)
Adjustments to reconcile net loss to net cash used in operating activities:
Preferred C shares issued in connection with a license agreement	140,000
Issuance of shares for services		17,000
Share-based compensation expense	17,883,554	2,959,731
Foreign currency loss (gain)	3,824,383	(1,676,117)
Depreciation	2,053,220	679,177
Amortization of interest on asset retirement obligation	(38,301)	19,313
Change in fair value of warrant liability	1,514,775	465,633
Convertible note inducement expense		553,500
Issuance of shares for acquired research and development expense	2,990,250
Issuance of note payable in connection with lease termination		1,442,009
Benefit for income taxes	(474,391)	0
(Increase) in operating assets:
Prepaid expenses	(35,465)	(669,756)
Other current assets	(3,684,465)	(493,424)
Security deposits	(115,573)
Increase (decrease) in operating liabilities:
Accounts payable	(2,119,493)	4,728,491
Accrued expenses	2,529,568	4,969,619
Due to Kadmon	(861,030)	317,992
Other liabilities	436,161
Deferred rent	(65,189)	(324,019)
Net cash used in operating activities	(58,887,870)	(18,055,386)
Cash flows from investing activities:
Purchase of property, plant and equipment	(11,258,479)	(10,535,717)
Net cash used in investing activities	(11,258,479)	(10,535,717)
Cash flows from financing activities:
Payments on capitalized lease obligation	(30,852)	(24,388)
Exercise of warrants	9,720,000
Proceeds from the sale of ordinary shares	69,750,000
Proceeds from the sale of convertible preferred C shares	56,849,594	16,854,653
(Payment) issuance of note payable	(1,442,009)	2,500,000
Proceeds from excercised stock options		9,950
Net cash provided by financing activities	130,040,415	19,340,215
Net increase (decrease) in cash, cash equivalents and restricted cash	59,894,066	(9,250,888)
Effect of exchange rate changes on cash	(362,529)	1,417
Cash, cash equivalents and restricted cash at beginning of year	8,672,014	17,921,485
Cash, cash equivalents and restricted cash at end of year	68,203,551	8,672,014
Supplemental disclosure of non-cash transactions:
Fixed asset acquisition included in accounts payable and accrued expenses at end of year	293,051	415,650
Issuance of convertible preferred C shares in connection with payables	1,356,129
Conversion of convertible preferred C shares into ordinary shares	120,520,391
Reclassification of warrant liability upon exercise of warrants	4,194,408
Capitalized lease obligation for equipment purchase		78,063
Asset retirement obligation in connection with a lease	(29,804)	(75,011)
Supplemental disclosure of cash flow information:
Cash paid for interest	34,546	20,894
Ordinary shares [Member]
Adjustments to reconcile net loss to net cash used in operating activities:
Share-based compensation expense	6,456,215
Cash flows from financing activities:
Issuance costs in connection with shares	(4,115,843)
Supplemental disclosure of non-cash transactions:
Issuance costs in connection with sale of ordinary shares in accounts payable and accrued expenses at end of period	441,779
Convertible Preferred C Shares [Member]
Cash flows from financing activities:
Issuance costs in connection with shares	$ (690,475)
Supplemental disclosure of non-cash transactions:
Conversion of note payable into convertible preferred C shares		$ 2,500,000