Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Revenues:
Collaboration revenue	$ 19,892	$ 5,904
Operating expenses:
Research and development	61,305	93,617	$ 96,718
General and administrative	37,780	50,850	44,464
Loss on lease termination	63,197
Total operating expenses	162,282	144,467	141,182
Loss from operations	(142,390)	(138,563)	(141,182)
Other income:
Other income and interest income, net	10,722	11,951	4,543
Net loss	$ (131,668)	$ (126,612)	$ (136,639)
Net loss per share, basic (in dollars per share)	$ (1.98)	$ (1.96)	$ (2.35)
Net loss per share, diluted (in dollars per share)	$ (1.98)	$ (1.96)	$ (2.35)
Weighted average common shares outstanding, basic (in shares)	66,624,249	64,483,520	58,114,893
Weighted average common shares outstanding, diluted (in shares)	66,624,249	64,483,520	58,114,893
Comprehensive loss:
Net loss	$ (131,668)	$ (126,612)	$ (136,639)
Other comprehensive (loss) income:
Unrealized gains (losses) on marketable securities	(115)	357	(83)
Comprehensive loss	$ (131,783)	$ (126,255)	$ (136,722)