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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Income [Member]
Accumulated Deficit [Member]
Total
Beginning balance at Dec. 31, 2021 $ 6 $ 689,866   $ (308,126) $ 381,746
Beginning balance, shares at Dec. 31, 2021 56,969,618        
Issuance of common stock upon exercise of stock options   102     102
Issuance of common stock upon exercise of stock options, shares 21,787        
Vesting of restricted common stock, shares 12,723        
Stock-based compensation expense   6,066     6,066
Net loss       (34,999) (34,999)
Ending balance at Mar. 31, 2022 $ 6 696,034   (343,125) 352,915
Ending balance, shares at Mar. 31, 2022 57,004,128        
Beginning balance at Dec. 31, 2022 $ 6 727,335 $ (83) (444,765) 282,493
Beginning balance, shares at Dec. 31, 2022 59,505,437        
Issuance of common stock in connection with the Moderna Agreement $ 1 22,555     22,556
Issuance of common stock in connection with the Moderna Agreement, shares 5,859,375        
Vesting of restricted common stock   (199)     (199)
Vesting of restricted common stock, shares 170,851        
Stock-based compensation expense   6,266     6,266
Unrealized losses on marketable securities     117   117
Net loss       (32,094) (32,094)
Ending balance at Mar. 31, 2023 $ 7 $ 755,957 $ 34 $ (476,859) $ 279,139
Ending balance, shares at Mar. 31, 2023 65,535,663