Accrued Expenses - Summary of Accrued expenses (Detail) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Accrued Expenses
Accrued employee compensation and benefits	$ 3,015	$ 7,970
Accrued external research and development expenses	2,406	1,959
Accrued professional fees	1,253	1,047
Property and equipment	388
Other	585	426
Total	$ 7,647	$ 11,402