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Property and equipment, net - Summary of Property and Equipment, Net (Detail) - USD ($)
$ in Thousands
Mar. 31, 2023
Dec. 31, 2022
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 37,857 $ 36,753
Less: Accumulated depreciation and amortization (15,827) (14,538)
Property and equipment, net 22,030 22,215
Laboratory equipment    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 13,595 13,619
Computer equipment and software    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 1,262 1,189
Furniture and fixtures    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 1,146 1,146
Leasehold Improvements    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross 20,786 20,786
Construction in progress    
Property, Plant and Equipment [Line Items]    
Property and equipment, gross $ 1,068 $ 13