X0306 4 2019-10-03 0 0001434418 CONSTELLATION PHARMACEUTICALS INC CNST 0001347769 COLUMN GROUP L P 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001614627 COLUMN GROUP GP, LP 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001707230 PONOI CAPITAL, LP 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001720702 Ponoi Management, LLC 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001732601 Ponoi Capital II, LP 1700 OWENS STREET STE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001746488 Ponoi II Management, LLC 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001182464 GOEDDEL DAVID V C/O COLUMN GROUP LP 1700 OWENS STREET, SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001614186 Kutzkey Tim 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001606074 Svennilson Peter 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 Common Stock 2019-10-03 4 P 0 1331764 8.5 A 6009702 D Common Stock 2019-10-03 4 P 0 80000 8.5 A 159155 I See footnote Consists of 665,882 shares of common stock held directly by Ponoi Capital, LP and 665,882 shares of common stock held directly by Ponoi Capital II, LP. Consists of 2,554,850 shares of common stock held directly by The Column Group, LP, 1,880,623 shares of common stock held directly by Ponoi Capital, LP and 1,574,229 shares of common stock held directly by Ponoi Capital II, LP. The reported number of shares held directly by Ponoi Capital, LP was decreased by one share to accurately match the issuer's records. The securities are directly held by The Column Group, LP, and indirectly held by The Column Group GP, LP, the general partner of The Column Group, LP. The managing partners of The Column Group GP, LP are David Goeddel and Peter Svennilson. The managing partners of The Column Group GP, LP may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. The securities are directly held by Ponoi Capital, LP, and indirectly held by Ponoi Management, LLC, the general partner of Ponoi Capital, LP. The managing partners of Ponoi Management, LLC are David Goeddel, Peter Svennilson, and Tim Kutzkey. The managing partners of Ponoi Management, LLC may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. The securities are directly held by Ponoi Capital II, LP, and indirectly held by Ponoi II Management, LLC, the general partner of Ponoi Capital II, LP. The managing partners of Ponoi II Management, LLC are David Goeddel, Peter Svennilson, and Tim Kutzkey. The managing partners of Ponoi II Management, LLC may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. The securities are held directly by The David V. and Alena Z. Goeddel 2004 Trust. Jennifer J. Carlson, Attorney-in-Fact 2019-10-07