X0306 4 2020-07-28 0 0001549595 Nurix Therapeutics, Inc. NRIX 0001347769 COLUMN GROUP L P 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001614627 COLUMN GROUP GP, LP 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 1 General Partner 0001600420 COLUMN GROUP II, LP 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001645333 Column Group II GP, LP 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 1 General Partner 0001707230 PONOI CAPITAL, LP 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001720702 Ponoi Management, LLC 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 1 General Partner 0001746488 Ponoi II Management, LLC 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 1 General Partner 0001732601 Ponoi Capital II, LP 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 0 0001614186 Kutzkey Tim 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 0 0 1 1 Managing Partner 0001182464 GOEDDEL DAVID V 1700 OWENS STREET SUITE 500 SAN FRANCISCO CA 94158 1 0 1 1 Managing Partner Common Stock 2020-07-28 4 C 0 600000 A 683333 D Common Stock 2020-07-28 4 C 0 875000 A 1558333 D Common Stock 2020-07-28 4 C 0 1836000 A 3394333 D Common Stock 2020-07-28 4 C 0 1989000 A 1989000 D Common Stock 2020-07-28 4 C 0 686274 A 686274 D Common Stock 2020-07-28 4 C 0 686274 A 686274 D Series A-1 Preferred Stock 2020-07-28 4 C 0 600000 0.00 D Common Stock 600000 0 D Series A-2 Preferred Stock 2020-07-28 4 C 0 875000 0.00 D Common Stock 875000 0 D Series B Preferred Stock 2020-07-28 4 C 0 1836000 0.00 D Common Stock 1836000 0 D Series B Preferred Stock 2020-07-28 4 C 0 1989000 0.00 D Common Stock 1989000 0 D Series D Preferred Stock 2020-07-28 4 C 0 686274 0.00 D Common Stock 686274 0 D Series D Preferred Stock 2020-07-28 4 C 0 686274 0.00 D Common Stock 686274 0 D The Series A-1 Preferred Stock, Series A-2 Preferred Stock, Series B Preferred Stock and Series D Preferred Stock automatically converted into shares of the Issuer's common stock on a one-for-one basis immediately upon the closing of the Issuer's initial public offering for no additional consideration and had no expiration date. The securities are directly held by The Column Group, LP ("TCG LP"), and indirectly held by The Column Group GP, LP ("TCG GP"), the general partner of TCG LP. The managing partners of TCG GP are David Goeddel and Peter Svennilson. The managing partners of TCG GP may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. The securities are directly held by The Column Group II, LP ("TCG II LP"), and indirectly held by The Column Group II GP, LP ("TCG II GP"), the general partner of TCG II LP. The managing partners of TCG II GP are David Goeddel and Peter Svennilson. The managing partners of TCG II GP may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. The securities are directly held by Ponoi Capital, LP ("Ponoi LP"), and indirectly held by Ponoi Management, LLC ("Ponoi LLC"), the general partner of Ponoi LP. The managing partners of Ponoi LLC are David Goeddel, Peter Svennilson and Tim Kutzkey. The managing partners of Ponoi LLC may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. The securities are directly held by Ponoi Capital II, LP ("Ponoi II LP"), and indirectly held by Ponoi II Management, LLC ("Ponoi II LLC"), the general partner of Ponoi II LP. The managing partners of Ponoi II LLC are David Goeddel, Peter Svennilson and Tim Kutzkey. The managing partners of Ponoi II LLC may be deemed to have voting and investment power with respect to such shares. Each individual managing partner disclaims beneficial ownership of these shares, except to the extent of his pecuniary interest in such shares. Due to SEC restrictions on the number of reporting owners, this is Form 1 of 2. /s/ Jennifer J. Carlson, Attorney-in-Fact 2020-07-29