X0306 4 2019-12-09 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL, INC. CRL 0001732091 Girshick Birgit 251 BALLARDVALE STREET WILMINGTON MA 01887 1 Corporate Executive VP Common Stock 2019-12-09 4 S 0 38 145.235 D 18728 D Common Stock 2019-12-09 4 S 0 50 145.245 D 18678 D Common Stock 2019-12-09 4 S 0 97 145.25 D 18581 D Common Stock 2019-12-09 4 S 0 80 145.26 D 18501 D Common Stock 2019-12-09 4 S 0 11 145.27 D 18490 D Common Stock 2019-12-09 4 S 0 118 145.28 D 18372 D Common Stock 2019-12-09 4 S 0 64 145.285 D 18308 D Common Stock 2019-12-09 4 S 0 50 145.29 D 18258 D Common Stock 2019-12-09 4 S 0 89 145.32 D 18169 D Common Stock 2019-12-09 4 S 0 60 145.33 D 18109 D Common Stock 2019-12-09 4 S 0 184 145.34 D 17925 D Common Stock 2019-12-09 4 S 0 100 146.51 D 17825 D Common Stock 2019-12-09 4 S 0 92 146.605 D 17733 D Common Stock 2019-12-09 4 S 0 18 146.79 D 17715 D This sale occurred pursuant to a 10b5-1 Trading Plan. /s/ Birgit Girshick 2019-12-09