X0306 4 2019-12-09 0001100682 CHARLES RIVER LABORATORIES INTERNATIONAL, INC. CRL 0001732091 Girshick Birgit 251 BALLARDVALE STREET WILMINGTON MA 01887 1 Corporate Executive VP Common Stock 2019-12-09 4 S 0 87 143.70 D 23973 D Common Stock 2019-12-09 4 S 0 96 143.73 D 23877 D Common Stock 2019-12-09 4 S 0 99 143.79 D 23778 D Common Stock 2019-12-09 4 S 0 95 143.855 D 23683 D Common Stock 2019-12-09 4 S 0 82 143.895 D 23601 D Common Stock 2019-12-09 4 S 0 69 143.905 D 23532 D Common Stock 2019-12-09 4 S 0 78 143.93 D 23454 D Common Stock 2019-12-09 4 S 0 94 143.935 D 23360 D Common Stock 2019-12-09 4 S 0 68 143.95 D 23292 D Common Stock 2019-12-09 4 S 0 82 143.96 D 23210 D Common Stock 2019-12-09 4 S 0 138 144.035 D 23072 D Common Stock 2019-12-09 4 S 0 92 144.11 D 22980 D Common Stock 2019-12-09 4 S 0 91 144.125 D 22889 D Common Stock 2019-12-09 4 S 0 92 144.15 D 22797 D Common Stock 2019-12-09 4 S 0 81 144.32 D 22716 D Common Stock 2019-12-09 4 S 0 84 144.33 D 22632 D Common Stock 2019-12-09 4 S 0 100 144.42 D 22532 D Common Stock 2019-12-09 4 S 0 100 144.44 D 22432 D Common Stock 2019-12-09 4 S 0 201 144.47 D 22231 D Common Stock 2019-12-09 4 S 0 105 144.54 D 22126 D Common Stock 2019-12-09 4 S 0 16 144.57 D 22110 D Common Stock 2019-12-09 4 S 0 11 144.58 D 22099 D Common Stock 2019-12-09 4 S 0 81 144.59 D 22018 D Common Stock 2019-12-09 4 S 0 100 144.605 D 21918 D Common Stock 2019-12-09 4 S 0 87 144.61 D 21831 D Common Stock 2019-12-09 4 S 0 10 144.625 D 21821 D Common Stock 2019-12-09 4 S 0 6 144.63 D 21815 D Common Stock 2019-12-09 4 S 0 1 144.65 D 21814 D Common Stock 2019-12-09 4 S 0 5 144.655 D 21809 D Common Stock 2019-12-09 4 S 0 169 144.66 D 21640 D This sale occurred pursuant to a 10b5-1 Trading Plan. /s/ Birgit Girshick 2019-12-09