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License Agreements - Additional Information (Details) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Sep. 30, 2019
Feb. 28, 2019
Mar. 31, 2018
Apr. 30, 2016
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Dec. 31, 2019
Dec. 31, 2017
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Upfront payment received $ 26,700,000                  
Research and development expense         $ 17,924,000 $ 12,497,000 $ 35,499,000 $ 21,046,000    
License and Service                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
License revenues         0   0      
License Agreement | Alexion | Japan                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Upfront nonrefundable payment received 25,000,000.0                  
License Agreement | Alexion                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Upfront payment received 25,000,000.0                  
License Agreement | Alexion | Cost of License Revenue                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Research and development expense                 $ 2,500,000  
License Agreement | Alexion | Japan                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Eligible amount receivable in regulatory milestone payment         30,000,000.0   30,000,000.0      
License Agreement | Alexion | Japan | Maximum                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Eligible amount receivable in regulatory milestone payment         30,000,000.0   30,000,000.0      
License Agreement | Stanford University                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Upfront license payment amount       $ 25,000            
Maximum potential payments upon achievement of specific intellectual property, clinical and regulatory milestone events and royalties payment on net sales       $ 1,000,000.0            
Period of annual decrease in license obligation amount due       3 years            
Research and development expense   $ 200,000 $ 50,000              
Milestone expense         $ 0.0 $ 0.0 $ 0.0 $ 200,000    
Percentage of non royalty amount payable             10.00%      
License Agreement | Stanford University | Research and Development                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
License fee paid                   $ 10,000
License Agreement | Stanford University | Common Stock                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Shares issued       56,809            
Stock Purchase Agreement | Alexion                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Aggregate purchase price of shares issued $ 25,000,000.0                  
Closing price $ 41.91                  
Upfront payment received $ 1,700,000                  
Stock Purchase Agreement | Alexion | Common Stock                    
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                    
Number of shares issued 556,173                  
Shares issued price per share $ 44.95