X0306 4 2020-12-02 0 0001731831 Eidos Therapeutics, Inc. EIDX 0001742587 Sinha Uma C/O EIDOS THERAPEUTICS, INC. 101 MONTGOMERY STREET, SUITE 2000 SAN FRANCISCO CA 94104 1 1 0 0 Chief Scientific Officer Common Stock 2020-12-02 4 S 0 3798 89.6267 D 317727 D Common Stock 2020-12-02 4 S 0 702 90.6339 D 317025 D Common Stock 2020-12-02 4 S 0 300 91.89 D 316725 D Common Stock 2020-12-02 4 S 0 200 92.965 D 316525 D This transaction was effected pursuant to a Rule 10b5-1 Sales Plan adopted by the Reporting Person on August 13, 2020. Represents the weighted average sale price of the shares sold ranging from $89.15 to $90.125 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes 2 through 5. Represents the weighted average sale price of the shares sold ranging from $90.33 to $91.18 per share. Represents the weighted average sale price of the shares sold ranging from $91.56 to $92.10 per share. Represents the weighted average sale price of the shares sold ranging from $92.71 to $93.22 per share. /s/ Franco Valle, Attorney-in-Fact 2020-12-03