X0306 4 2019-03-19 0 0001731831 Eidos Therapeutics, Inc. EIDX 0001743029 Siu Christine C/O EIDOS THERAPEUTICS, INC. 101 MONTGOMERY STREET, SUITE 2550 SAN FRANCISCO CA 94104 0 1 0 0 CFO and Secretary Common Stock 2018-11-30 5 A 0 E 1081 12.01 A 1081 D Common Stock 2019-03-19 4 M 0 10871 0.15 A 11952 D Common Stock 2019-03-19 4 M 0 34662 0.59 A 46614 D Common Stock 2019-03-19 4 S 0 11913 19.66 D 34701 D Stock Option (right to buy) 0.15 2019-03-19 4 M 0 10871 0.00 D 2017-03-06 2027-03-05 Common Stock 10871 0 D Stock Option (right to buy) 0.59 2019-03-19 4 M 0 34662 0.00 D 2027-12-21 Common Stock 34662 244191 D Shares acquired pursuant to the Issuer's 2018 Employee Stock Purchase Plan. Represents the weighted average sale price of the shares sold ranging from $19.65 to $20.00 per share. The Reporting Person will provide, upon request by the Commission staff, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price. The shares subject to this option vest and become exercisable in 48 equal monthly installments after December 1, 2017, subject to the Reporting Person's continuous service to the Issuer through each such vesting date. /s/ Franco Valle, Attorney-in-Fact 2019-03-21