X0306 4 2018-12-04 0 0001731831 Eidos Therapeutics, Inc. EIDX 0001574558 Lis William C/O EIDOS THERAPEUTICS, INC. 101 MONTGOMERY STREET, SUITE 2550 SAN FRANCISCO CA 94104 1 0 0 0 Stock Option (right to buy) 13.67 2018-12-04 4 A 0 43056 0.00 A 2028-12-04 Common Stock 43056 43056 D The option grant was approved by the Issuer's board of directors on December 4, 2018, and is subject to cancellation if the Issuer's shareholders do not approve an increase to the share reserve of the stock option plan under which the option was granted by December 4, 2019. The Reporting Person is a participant in the Issuer's 2018 Stock Option and Incentive Plan and received 43,056 stock options (the "Grant") on December 4, 2018. The Grant shall vest as follows: one-third of the stock options shall vest annually over a period of three (3) years following December 4, 2018 subject to the Reporting Person's continued service to the Issuer through each vesting date. /s/ Franco Valle, Attorney-in-Fact 2018-12-07