X0508 4 2024-12-11 0001704292 Zai Lab Ltd ZLAB 0001731790 Du Ying C/O ZAI LAB LIMITED 314 MAIN STREET, 4TH FLOOR, SUITE 100 CAMBRIDGE MA 02142 true true Chairperson & CEO false American Depositary Shares 2024-12-11 4 G 0 500000 0 D 494117 D Each American Depositary Share ("ADS") represents ten Ordinary Shares of the issuer. Our ADSs and Ordinary Shares are fully fungible. For purposes of this Form 4, we are reporting this in terms of ADSs. This transaction represents a bona fide gift to a grantor retained annuity trust for which there is an independent trustee. /s/ Bruce Blefeld, Attorney-in-Fact 2024-12-13