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Accrued Expenses and Other Liabilities
6 Months Ended
Jun. 30, 2021
Payables and Accruals [Abstract]  
Accrued Expenses and Other Liabilities Accrued Expenses and Other Liabilities
Accrued expenses and other liabilities consisted of the following (in thousands):
June 30, 2021December 31, 2020
Compensation and benefits
$8,833 $8,732 
Research and development costs
11,373 15,343 
UCLB milestone and option
— 205 
Professional fees
2,289 3,005 
Other liabilities
678 496 
Total accrued expenses and other liabilities
$23,173 $27,781 
The decrease in accruals of $4.0 million in research and development costs is related to usage of the accruals for raw materials and services for clinical projects combined with a decrease in accruals for purchases of lab equipment related to the scaling of manufacturing.