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In-license, Acquisition and Collaboration Agreements - MedImmune License Agreement (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Jul. 31, 2020
Sep. 30, 2017
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2017
License and Acquisition Agreements              
Notice period to terminate the agreement by both parties for material breaches   90 days          
Research and development     $ 16,485 $ 19,236 $ 51,100 $ 71,864  
MedImmune | License Agreement              
License and Acquisition Agreements              
Remaining milestone payments to be paid upon clinical and regulatory milestone achievement     57,500   57,500    
Annual net sales excluded from calculation of specified annual net sales thresholds $ 1,000,000            
Maximum percentage of royalty payable on annual net sales of licensed products 20.00%            
Notice period to terminate the agreement by both parties for material breaches 90 days            
Notice period to terminate the agreement 90 days            
Research and development     $ 0 $ 0 $ 0 $ 0  
Minimum | MedImmune | License Agreement              
License and Acquisition Agreements              
Additional specified annual net sales threshold for additional milestone payment. $ 1,000,000            
Maximum | MedImmune | License Agreement              
License and Acquisition Agreements              
Milestone payment to be paid upon specified milestone achievements for first two indications             $ 72,500
Milestone payment to be paid upon clinical and regulatory milestone achievement             $ 15,000
Milestone payment to be paid upon specified annual sales milestone achievements 85,000            
Additional specified annual net sales threshold for additional milestone payment. $ 1,100,000