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Net Loss per Share - Anti-Dilutive Securities (Details) - shares
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Anti-dilutive securities excluded from computation of earnings per share      
Total, anti-dilutive securities excluded from computation of earnings per share 10,164,170 8,820,030 6,838,158
Stock options      
Anti-dilutive securities excluded from computation of earnings per share      
Total, anti-dilutive securities excluded from computation of earnings per share 9,958,858 8,491,734 5,960,939
Restricted shares      
Anti-dilutive securities excluded from computation of earnings per share      
Total, anti-dilutive securities excluded from computation of earnings per share     877,219
Restricted Share Units (RSUs)      
Anti-dilutive securities excluded from computation of earnings per share      
Total, anti-dilutive securities excluded from computation of earnings per share 205,312 328,296